News

Addgene podcast post - 6 Feb 2018
Channel NewsAsia - Why It Matters S4 - Should We Hack Our Genes?
President's Science and Technology Awards - Young Scientist Award 2020 video
President's Science and Technology Awards - Young Scientist Award 2020 - The Straits Times
CNA Channel NewsAsia Interview video - 18 Dec 2020
C-to-G Base Editor Press Release - 4 Mar 2021
PRECISE - Rewriting the Human Genome
A Fulfilling Career in Applied Research with A*STAR
Gene editing cuts to the chase
Rewriting genetic risk: His quest to prevent inherited diseases
On a quest to outsmart genetic diseases
Editing the basics

Alumni features
Fostering Innovation for a Transformative Future
Rewriting the rules of DNA repair



We are supported by:

Publications

Google Scholar
Pubmed

Research


Our team builds technologies for a world without diseases. We build technologies so that we can engineer DNA, make pinpoint changes to genes with CRISPR, deliver treatments with adeno-associated viruses (AAVs), make safer therapeutics that bypass adverse immune reactions, fight diseases, and save lives. Our overarching motivation is to establish safe and efficacious genome therapeutics for routine human use.

This is how we create new medicines. This is how we engineer life.

Team

Wei Leong CHEW
Wei Leong CHEW | Principal Investigator
Ph.D. | Harvard University
B.S. | Duke University
Email

GUO Ke
GUO Ke | Assistant Lab Manager
Ph.D. | University of Berne
B.S. | Henan Medical University
Email

Eddie KENG Choong Tat
Eddie KENG Choong Tat | Research Associate
Ph.D. | National University of Singapore
M.Sc. | Nanyang Technological University, Singapore
B.S. | National University of Singapore
Email

Daryl LIM
Daryl LIM | Research Officer
B.S. | National University of Singapore
Email

Amine MELIANI
Amine MELIANI | Postdoctoral Fellow
PhD | Sorbonne University; Genethon
Masters | Paris Descartes University; AgroParisTech
BSc | University of Algiers
Email

Kimberle SHEN
Kimberle SHEN | Research Fellow (NSS BS-PhD)
PhD | Stanford University
BA | University of Cambridge
Email

Samantha SEAH
Samantha SEAH | Research Fellow (NSS BS-PhD)
PhD | EMBL Heidelberg
BA | University of Cambridge
Email

WANG Bolun
WANG Bolun | Postdoctoral Fellow
PhD | Peking University
BEng | Xi’an Jiaotong University
Email


Alumni

Jonell TAN
Jonell TAN | Attachment Student
BSc | Nanyang Technological University

YONG Fong Sin
YONG Fong Sin | Attachment Student
BSc | National University of Singapore

Eunice HO
Eunice HO | Attachment Student (NSS)
BA/MBiol | University of Oxford

HEW Yu Heng
HEW Yu Heng | Attachment Student
BA | University of Cambridge

Caleigh Mei TAN
Caleigh Mei TAN | Attachment Student
B.S. | De La Salle University

Sharmada TOTAPALLY
Sharmada TOTAPALLY | Attachment Student
BEng | National University of Singapore

Robin XIONG
Robin XIONG | Attachment Student (SIPGA)
BS | Massachusetts Institute of Technology

Corina MOTOFEANU
Corina MOTOFEANU | Graduate Student (SINGA)
BSc | University of Manchester

CHIA Bing Shao
CHIA Bing Shao | Research Fellow (NSS BS-PhD)
PhD | Harvard University
MS | Johns Hopkins University
BS | Johns Hopkins University

CHEN Liwei
CHEN Liwei | Research Officer
M.Sc. | Harvard University
B.S. | University of Chicago

Hong-Ting PREKOP
Hong-Ting PREKOP | Programme Manager
Ph.D. | King’s College London
MRes | Imperial College London
B.A. | University of Cambridge

Joshua JAMES
Joshua JAMES | Graduate Student (ARAP - University of Manchester)
MSci | University of Bristol

Diya SRIVASTAVA
Diya SRIVASTAVA | Research Officer
BSc | University of Sydney

Reyner JUSUF
Reyner JUSUF | Attachment Student
BSc | University College London

Drishtant CHAKRABORTY
Drishtant CHAKRABORTY | Attachment Student
BSc | University of Cambridge

Nicholas ONG
Nicholas ONG | Senior Research Fellow (NSS BS-PhD)
Ph.D. | Rice University
B.S. | Duke University

Benjamin WEBB
Benjamin WEBB | Senior Research Fellow
PhD | Imperial College London

KOH Zhi Kai
KOH Zhi Kai | Attachment Student
BSc | Nanyang Technological University

Charmaine TAN Zi Yun
Charmaine TAN Zi Yun | Attachment Student
BSc | University of California Los Angeles

Linette LUM Hui Min
Linette LUM Hui Min | Attachment Student
BSc | King’s College London

Mika THAM Ni Ya
Mika THAM Ni Ya | Attachment Student
BSc | University College London

YANG Qize
YANG Qize | Attachment Student (NSS BS 8-week)
BSc | Cambridge University

Lavina Sierra TAY
Lavina Sierra TAY | Programme Manager
Assistant Head | National Research Foundation, Singapore
PhD | National University of Singapore
BSc | University of Western Australia

June PARK Jung Eun
June PARK Jung Eun | Postdoctoral Fellow
PhD | Seoul National University
BSc | Seoul Women’s University

Lekha RAVICHANDRAPRABHU
Lekha RAVICHANDRAPRABHU | Research Officer
B.Eng. | Nanyang Technological University

MUHAMMAD Irfan Bin Hajis
MUHAMMAD Irfan Bin Hajis | Research Officer
B.Sc. | Nanyang Technological University

CHOI Yook Wah
CHOI Yook Wah | Research Officer
B.Sc. | University of Nevada, Reno

Derek CHAN
Derek CHAN | Research Officer
B.Sc. | University of Queensland

Izavel LEE
Izavel LEE | Student Intern (NSS 8-week)
B.A. | University of Cambridge

Anna Traczyk
Anna TRACZYK | Postdoctoral Fellow
Ph.D. | Nanyang Technological University
Master’s | Warsaw University of Technology
B.S. | Warsaw University of Technology

Priscilla RAJAKUMAR
Priscilla RAJAKUMAR | Postdoctoral Fellow
PhD | University College London
Masters | University of Malaya
Bachelor | Kolej Universiti Sains dan Teknologi Malaysia

GOH Chen Gang
GOH Chen Gang | Research Officer (NSS)
B.Sc. | Imperial College London

Amanda LOH
Amanda LOH | RAOS Awardee; Student
Current student at University College London

Hannah NICHOLAS
Hannah NICHOLAS | Programme Manager, Apr 2019 - Mar 2020
Senior Lecturer in Molecular Biology (Tenured research and teaching) | University of Sydney
DPhil | University of Oxford
BMedSci | University of Sydney

Peter Jim PAA
Peter Jim PAA | Graduate Student (SINGA)
B.S. (First Class) | University of Manitoba
B.S. | University of the Philippines

Swathi Nachiar MANIVANNAN
Swathi Nachiar MANIVANNAN | Student Intern (NSS 8-week), Jul 2019 - Aug 2019
B.A. | University of Cambridge

HWANG Xueyan
HWANG Xueyan | Student Intern, Jul 2019 - Aug 2019
B.A. | University of Cambridge

CHEW Yi Ting
CHEW Yi Ting | Student Intern (NSS 8-week), Jun 2019 - Aug 2019
B.A. | University of Cambridge

Sabranth GUPTA
Sabranth GUPTA | Student Intern, Feb 2019 - Aug 2019
B.Tech. | Vellore Institute of Technology

Jerry TAN Wei Heng
Jerry TAN Wei Heng | Student Intern, Feb 2019 - Jul 2019
Commencing undergraduate studies

LEE Swee Leng
LEE Swee Leng | Student Intern, Feb 2019 - Jul 2019
Commencing undergraduate studies

CHOK Kian Chung
CHOK Kian Chung | Student Intern, Dec 2018 - Mar 2019
B.S. | International Medical University

Suraj VASANDANI
Suraj VASANDANI | Student Intern, Jun 2018 - Jun 2019
B.S. | Atma Jaya Catholic University

Franciscus Asisi ATMADI
Franciscus Asisi ATMADI | Student Intern, May 2018 - Aug 2018
B.S. | National University of Singapore

KIM Sung Hwan
KIM Sung Hwan | SIPGA Student, Dec 2017 - Feb 2018
M.Sc. | Seoul National University
B.S. | Hanyang University

Bagus SARMITO
Bagus SARMITO | Student Intern, Jun 2017 - Jun 2018
B.S. | Atma Jaya Catholic University

GOH Si Wei
GOH Si Wei | Research Officer, Jun 2017 - Jun 2019
B.S. | National University of Singapore

* We are recruiting talented postdocs and research officers.
We mentor students through A*STAR scholarships and inter-institutional collaborations.
Email and come chat!

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chewlab.github.io

The Chew Lab at Genome Institute of Singapore.

We build technologies to rewrite the human genome Our research broadly covers synthetic biology and technology development, with focus on genome-editing, CRISPR-Cas9, AAV, immunology, and gene therapy. To invent genome engineering technologies, we capitalize on nucleic acid manipulation, protein engineering, directed evolution, and high-throughput methodologies. Our overarching motivation is to establish safe and efficacious genome therapeutics for routine human use.
  • Wei Leong Chew